Indole-4-carboxaldehyde-13C is the 13C-labeled Indole-4-carboxaldehyde (HY-W001288). Indole-4-carboxaldehyde is an ergot alkaloid precursor. Indole-4-carboxaldehyde attenuates the methylglyoxal (MGO)-induced expression of inflammatory-related genes, such asTNF-alpha and IFN-gamma by activating NF-kappaB without toxicity in HepG2 cells. Indole-4-carboxaldehyde reduces the MGO-induced AGE formation and the expression of the receptor for AGE (RAGE). Indole-4-carboxaldehyde can be used for the study of hepatic steatosis[1][2].
Molekulargewicht:
146.15
Formel:
C8 13CH7NO
Target-Kategorie:
Isotope-Labeled Compounds,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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