Fmoc-(R)-2-(7-octenyl) Ala-OH is an unnatural Fmoc-protected amino acid and modification module. Fmoc-(R)-2-(7-octenyl) Ala-OH serves as a key building block for all-hydrocarbon cross-linking modification of antimicrobial peptides, and facilitates the generation of stapled peptide derivatives. When introduced into specific sites of the parent peptide, Fmoc-(R)-2-(7-octenyl) Ala-OH effectively increases the alpha-helix content of the peptide chain, thereby significantly enhancing its antimicrobial activity and proteolytic stability. Fmoc-(R)-2-(7-octenyl) Ala-OH is widely used in research on bacterial infections and the development of related antimicrobial agents[1][2].Stapled peptide is a specially chemically modified polypeptide. It locks the peptide chain into a stable alpha-helical structure by introducing a staple-like chemical bridge (usually an all-carbon backbone) at specific positions of the peptide chain.
Molekulargewicht:
421.53
Reinheit:
99.43
CAS Nummer:
[945212-26-0]
Formel:
C26H31NO4
Target-Kategorie:
Amino Acid Derivatives
Anwendungsbeschreibung:
MCE Product type: Peptides
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