7,8-Dihydro-L-biopterin is a NOS uncoupling inducer with blood-brain barrier permeability, and it is a reduced non-conjugated pteridine. 7,8-Dihydro-L-biopterin is the main metabolite of 4-amino-tetrahydro-L-biopterin, and it undergoes photooxidation to form biopterin. 7,8-Dihydro-L-biopterin promotes the conversion of nitric oxide synthase to a superoxide-producing form, thereby increasing oxidative stress levels in the renal outer medulla and inducing apoptosis. 7,8-Dihydro-L-biopterin is sensitive to the inhibitory effect of SOD, and it can be applied to research related to salt-sensitive hypertension, moderate to severe traumatic brain injury, and neurodegenerative diseases[1][2][3][4].
Molekulargewicht:
239.23
Reinheit:
99.79
CAS Nummer:
[6779-87-9]
Formel:
C9H13N5O3
Target-Kategorie:
Apoptosis,NO Synthase,SOD
Anwendungsbeschreibung:
MCE Product type: Natural Products
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