Suberoyl bis-hydroxamic acid (Suberohydroxamic acid, SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 µM and 0.30 µM, respectively[1].Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways[2].Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC)[3].
Molekulargewicht:
204.22
Reinheit:
98
CAS Nummer:
[38937-66-5]
Formel:
C8H16N2O4
Target-Kategorie:
Apoptosis,HDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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