Uridine 5-diphosphate sodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM, pEC50=6.52) and a potent P2Y14 antagonist (pEC50=7.28). Uridine 5-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis[1][2].