Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Molekulargewicht:
245.32
Reinheit:
98
CAS Nummer:
[60142-89-4]
Formel:
C12H23NO4
Target-Kategorie:
PROTAC Linkers
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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