3'-Deoxyuridine is a 3-deoxynucleoside analog and a 2,3-dideoxynucleoside. 3'-Deoxyuridine does not inhibit the replication of HCV-like RNA templates or luciferase levels in human cells at the tested concentrations. 3'-Deoxyuridine serves as a substrate for microbial dideoxyribosylation reactions to generate various 2,3-dideoxynucleosides, but cannot be converted into 2,3-dideoxycytidine by resting E. coli AJ 2595 cells. 3'-Deoxyuridine can be formed by the deamination of 3-deoxycytidine by E. coli BM-11 cytidine deaminase, and can also undergo phosphorolytic cleavage to produce uracil and the corresponding pentose phosphate. 3'-Deoxyuridine has been used in research related to HCV and other relevant fields[1][2][3].
Molekulargewicht:
228.20
Reinheit:
99.76
CAS Nummer:
[7057-27-4]
Formel:
C9H12N2O5
Target-Kategorie:
HCV
Anwendungsbeschreibung:
MCE Product type: Reference compound
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