trans-Aconitic acid is an orally active aconitase inhibitor that non-competitively inhibits the conversion of citric acid to cis-aconitic acid and competitively inhibits the conversion of cis-aconitic acid to isocitric acid. trans-Aconitic acid inhibits the growth of Leishmania donovani promastigotes, the transformation of Leishmania donovani amastigotes to promastigotes, and the in vitro proliferation of Leishmania donovani amastigotes within macrophages in vitro. trans-Aconitic acid can be used in research related to visceral leishmaniasis (kala-azar)[1][2][3][4].
Molekulargewicht:
174.11
Reinheit:
99.74
CAS Nummer:
[4023-65-8]
Formel:
C6H6O6
Target-Kategorie:
Parasite
Anwendungsbeschreibung:
MCE Product type: Natural Products
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