5-Hydroxymethylcytosine, CAS [[1123-95-1]]

Produktübersicht

• Artikelname: 5-Hydroxymethylcytosine, CAS [[1123-95-1]]
• Artikelnummer: MCE-HY-W018324
• Hersteller Artikelnummer: HY-W018324
• Alternativnummer: MCE-HY-W018324-5MG,MCE-HY-W018324-10MG,MCE-HY-W018324-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 5hmC

Produktbeschreibung

5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development. 5-Hydroxymethylcytosine can be used for the study of non-small cell lung cancer (NSCLC), neurodegenerative diseases (Alzheimers, Parkinsons) and hematological malignancies (acute myeloid leukemia, myelodysplastic syndromes)[1][2].

Produkteigenschaften

• Molekulargewicht: 141.13
• Reinheit: 99.91
• CAS Nummer: [1123-95-1]
• Formel: C5H7N3O2
• Target-Kategorie: Endogenous Metabolite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound