Tetrachloroauric acid is an Au (III) compound and bilayer disruptor that can be used to damage red blood cells. Tetrachloroauric acid specifically disrupts the bilayer structure of representative phospholipids (dimyristoylphosphatidylcholine and dimyristoylphosphatidylethanolamine) in human red blood cell membranes, and induces morphological changes in intact human red blood cells. Tetrachloroauric acid causes downregulation of MT I-II and GFAP expression in the mouse brain following chronic treatment. Tetrachloroauric acid is being used in studies related to neurotoxicity and hematotoxicity, including analyses of human red blood cells and molecular models of red blood cell membranes, as well as immunohistochemical evaluation of the mouse brain[1].
Molekulargewicht:
339.79
Reinheit:
97
CAS Nummer:
[16903-35-8]
Formel:
HAuCl4
Target-Kategorie:
Biochemical Assay Reagents
Anwendungsbeschreibung:
MCE Product type: Reference compound
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