Saccharopine (L-Saccharopine) hydrochloride, a lysine degradation intermediate, is a mitochondrial toxin. Lysine and alpha-ketoglutarate are converted into Saccharopine hydrochloride by the lysine-ketoglutarate reductase. Saccharopine hydrochloride is then oxidized to alpha-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine hydrochloride impairs development by disrupting mitochondrial homeostasis[1][2][3].
Molekulargewicht:
312.75
Reinheit:
99.84
Formel:
C11H21ClN2O6
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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