Olopatadine-d6, CAS [[1231979-85-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: Olopatadine-d6, CAS [[1231979-85-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-W062109S
• Hersteller Artikelnummer: HY-W062109S
• Alternativnummer: MCE-HY-W062109S-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Olopatadine-d6 is the deuterium labeled Olopatadine. Olopatadine hydrochloride (ALO4943A, KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4+ and CD8+ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis[1][2][3].

Produkteigenschaften

• Molekulargewicht: 343.45
• CAS Nummer: [1231979-85-3]
• Formel: C21H17D6NO3
• Target-Kategorie: CXCR,Histamine Receptor,Isotope-Labeled Compounds

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Isotope-Labeled Compounds