NITD-304 is an orally active anti-tuberculosis agent. NITD-304 exerts inhibitory and bactericidal activities gainst Mycobacterium tuberculosis and multidrug-resistant Mycobacterium tuberculosis. NITD-304 inhibits mycobacterial cell wall biosynthesis and demonstrates synergistic or additive growth inhibitory activity with select antibacterial agents. NITD-304 shows low risk of cardiotoxicity and drug-drug interactions, with no inhibition of major cytochrome P-450 enzymes or hERG channel. NITD-304 can be used for the research of tuberculosis and multidrug-resistant tuberculosis[1][2].
Molekulargewicht:
339.26
CAS Nummer:
[1473450-60-0]
Formel:
C17H20Cl2N2O
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound2
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