Alloc-Val-Ala-PAB is a peptide cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Ala will specifically be cleaved by Cathepsin B. The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer.
Molekulargewicht:
377.43
Reinheit:
99.61
CAS Nummer:
[1343407-91-9]
Formel:
C19H27N3O5
Target-Kategorie:
ADC Linker
Anwendungsbeschreibung:
MCE Product type: Reference compound
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