4-Chloropyridine, CAS [[626-61-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W093017
Hersteller Artikelnummer:
HY-W093017
Alternativnummer:
MCE-HY-W093017-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
4-Chloropyridine is an inhibitor of nicotinamide N-methyltransferase (NNMT). It can act as a substrate for NNMT and, during its catalytic reaction, enhances the electrophilicity of the C4 position by methylating the nitrogen atom of the pyridine ring. This promotes an aromatic nucleophilic substitution reaction with the non-catalytic cysteine (C159) in NNMT, ultimately leading to the suicide inhibition of NNMTs activity. 4-Chloropyridine holds potential for the development of NNMT activity-based probes [1].
Molekulargewicht:
113.54
CAS Nummer:
[626-61-9]
Formel:
C5H4ClN
Target-Kategorie:
Amine N-methyltransferase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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