Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-beta (TGF-beta) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-beta signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs)[1][2].
Molekulargewicht:
488.59
Reinheit:
99.94
CAS Nummer:
[608-71-9]
Formel:
C6HBr5O
Target-Kategorie:
Apoptosis,TGF-beta/Smad
Anwendungsbeschreibung:
MCE Product type: Reference compound
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