3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17beta-HSD1 at 6 µM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis[1].
Molekulargewicht:
204.18
CAS Nummer:
[10441-27-7]
Formel:
C11H8O4
Target-Kategorie:
17beta-HSD
Anwendungsbeschreibung:
MCE Product type: Reference compound
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