2-Chloro-2-deoxy-D-glucose, a 2-substituted Glucose (HY-B0389) analogue. 2-Chloro-2-deoxy-D-glucose inhibits the growth of P. falciparum. 2-Chloro-2-deoxy-D-glucose inhibits phosphorylation of [14C]2-deoxy-D-glucose by parasite hexokinase, induces trophozoite cytosol acidification, reduces [14C]2-deoxy-D-glucose uptake. 2-Chloro-2-deoxy-D-glucose can be used for the research of malaria[1][2].
Molekulargewicht:
198.60
Reinheit:
99.35
CAS Nummer:
[14685-79-1]
Formel:
C6H11ClO5
Target-Kategorie:
Hexokinase,Parasite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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