7alpha,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC), it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7alpha,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7alpha,27-di-OHC exists as a structural isomer of 7alpha,25-dihydroxycholesterol (7alpha25-OHC).
Molekulargewicht:
418.65
Reinheit:
99.9
CAS Nummer:
[4725-24-0]
Formel:
C27H46O3
Target-Kategorie:
EBI2/GPR183,Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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