Xanthomicrol is extracted from the resin of the plant called Chinese bellflower (a member of the Scrophulariaceae family) and is a monoamine oxidase (MAOs) inhibitor. Xanthomicrol has anti-tumor and anti-inflammatory properties, with IC50 values of 0.88 and 1.69 µg/mL in HL60 and K562 cells. Xanthomicrols the main metabolite of 5DT in mouse colon, and it can reduce levels of iNOS protein and mRNA, as well as COX-2 protein levels. Additionally, Xanthomicrol decreases the production of the pro-inflammatory cytokine IL-1beta and induces the expression of the antioxidant enzyme HO-1[1][2][3][4][5].
Molekulargewicht:
344.32
Reinheit:
97.68
CAS Nummer:
[16545-23-6]
Formel:
C18H16O7
Target-Kategorie:
COX,Interleukin Related,NO Synthase,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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