DPQ (hydrochloride), CAS [[84050-22-6]] Preis auf Anfrage

Artikelnummer: MCE-HY-W424851
Artikelname: DPQ (hydrochloride), CAS [[84050-22-6]] Preis auf Anfrage
Artikelnummer: MCE-HY-W424851
Hersteller Artikelnummer: HY-W424851
Alternativnummer: MCE-HY-W424851-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine (hydrochloride)
DPQ hydrochloride is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD+/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ hydrochloride inhibits NF-kappaB pathway activation, reduces the expression of pro-inflammatory factors (such as TNF-alpha, IL-6) and oxidative stress. DPQ hydrochloride can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases[1][2][3].
Molekulargewicht: 325.79
CAS Nummer: [84050-22-6]
Formel: C14H20ClN5O2
Target-Kategorie: PARP
Anwendungsbeschreibung: MCE Product type: Reference compound