Thalidomide-NH-(CH2)3-NH-Boc, CAS [[2093386-36-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W584515
Hersteller Artikelnummer:
HY-W584515
Alternativnummer:
MCE-HY-W584515-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Thalidomide-NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11beta-substituted estradiol.