gamma-Eudesmol ((+)-gamma-Eudesmol) is a mitochondrial-mediated apoptosis inducer. gamma-Eudesmol binds mitochondrial membrane proteins, triggering depolarization of mitochondrial membrane potential and activating caspase cascades. gamma-Eudesmol demonstrates cytotoxicity against multiple tumor cell lines (e.g., HepG2, B16-F10) with IC50 values ranging from 8.86-15.15 µg/mL. gamma-Eudesmol is promising for research of cancers, such as hepatocellular carcinoma and melanoma[1][2][3].
Molekulargewicht:
222.37
CAS Nummer:
[1209-71-8]
Formel:
C15H26O
Target-Kategorie:
Apoptosis
Anwendungsbeschreibung:
MCE Product type: Reference compound
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