alpha-Androstenol (5alpha-Androst-16-en-3alpha-ol) is a steroid pheromone that has been found in boar testes and human male axillary sweat. alpha-Androstenol is also a positive modulator of GABAA receptors, which enhances GABA-activated currents in primary mouse cerebellar granule cells (EC50=0.4 µM). alpha-Androstenol decreases immobility time in the forced swim test and increases time spent in the open arms of the elevated plus maze in mice. alpha-Androstenol protects against seizures induced by Pentylenetetrazole or electroshock with anxiolytic-like activity in mice[1][2][3].
Molekulargewicht:
274.44
Reinheit:
99.85
CAS Nummer:
[1153-51-1]
Formel:
C19H30O
Target-Kategorie:
GABA Receptor
Anwendungsbeschreibung:
MCE Product type: Natural Products
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