VU0469650 hydrochloride is a brain-penetrant negative allosteric modulator of metabotropic glutamate receptor 1 (mGluR1). VU0469650 hydrochloride inhibits glutamate-induced calcium flux in cells expressing human mGluR1 (IC50= 99 nM). VU0469650 hydrochloride is promising for research of central nervous system diseases such as anxiety, addiction, and epilepsy[1].
Molekulargewicht:
400.94
Formel:
C22H29ClN4O
Target-Kategorie:
mGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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