Bromuconazole, CAS [[116255-48-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W715812
Hersteller Artikelnummer:
HY-W715812
Alternativnummer:
MCE-HY-W715812-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Bromuconazole is a triazole fungicide with oral efficacy and blood-brain barrier permeability. Bromuconazole protects crops from various fungal contaminations. Bromuconazole exhibits cytotoxicity against a variety of cancer cells, induces G0/G1 cell cycle arrest and inhibits DNA synthesis in cancer cells, and triggers cytoskeletal structural disorder, genotoxic damage, apoptotic (apoptosis) cell death, and mitochondrial membrane depolarization. Bromuconazole activates caspase-3, induces excessive production of ROS, p53 and Bax, lipid peroxidation, increased activities of SOD and CAT, and downregulates Bcl-2. By upregulating p-ERK1/2 and p-JNK, Bromuconazole disrupts the MAPK signaling pathway, impairs the cellular stress response of human trophoblast cells and endometrial cells, and damages the implantation process. Bromuconazole is applicable to research related to glioma, colon cancer, reproductive injury (implantation dysfunction), and cardiac dysfunction[1][2][3][4][5][6][7].
Molekulargewicht:
377.06
CAS Nummer:
[116255-48-2]
Formel:
C13H12BrCl2N3O
Target-Kategorie:
Apoptosis,Bcl-2 Family,Caspase,Fungal,JNK,MDM-2/p53,p38 MAPK,PERK,Reactive Oxygen Species (ROS),SOD
Anwendungsbeschreibung:
MCE Product type: Reference compound
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