Trimethylamine oxide-15N is the deuterium labeled Trimethylamine N-oxide (HY-116084). Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-beta/smad2 signaling pathway[1][2][3].
Molekulargewicht:
76.10
Reinheit:
99.93
Formel:
C3H9 15NO
Target-Kategorie:
Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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