O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin (HY-14397). It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 µM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase. It has also been used in the synthesis of prostaglandin D2 (HY-101988) receptor antagonists.
Molekulargewicht:
205.21
CAS Nummer:
[50995-53-4]
Formel:
C11H11NO3
Target-Kategorie:
COX,Prostaglandin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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