(R)-Colchicine, CAS [[75520-89-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W741136
Hersteller Artikelnummer:
HY-W741136
Alternativnummer:
MCE-HY-W741136-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
(R)-Colchicine is the R-isomer of Colchicine (HY-16569). Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the alpha3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research[1][2][3][4][5].
