Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. Pipernonaline activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates reactive oxygen species (ROS) production, increased intracellular Ca(2+), and mitochondrial membrane depolarization[1].
Molekulargewicht:
341.44
Reinheit:
99.30
CAS Nummer:
[88660-10-0]
Formel:
C21H27NO3
Target-Kategorie:
Apoptosis,Caspase
Anwendungsbeschreibung:
MCE Product type: Natural Products
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