Midostaurin-13C6 Preis auf Anfrage
Artikelnummer:
MCE-HY-W751179
| Artikelname: |
Midostaurin-13C6 Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-W751179 |
| Hersteller Artikelnummer: |
HY-W751179 |
| Alternativnummer: |
MCE-HY-W751179-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| Alternative Synonym: |
PKC412-13C6, CGP 41251-13C6 |
| Midostaurin-13C6 (PKC412-13C6) is the 13C-labeled Midostaurin (HY-10230). Midostaurin (PKC412, CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCalpha/beta/gamma, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRbeta and VEGFR1/2 with IC50s ranging from 22-500 nM[1][2]. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects[3]. |
| Molekulargewicht: |
576.59 |
| Formel: |
C29 13C6H30N4O4 |
| Target-Kategorie: |
Apoptosis,c-Kit,Isotope-Labeled Compounds,NO Synthase,PKC,VEGFR |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
