O-Desmethyl midostaurin-13C6 (CGP62221-13C6, O-Desmethyl PKC412-13C6) is the 13C-labeled O-Desmethyl Midostaurin (HY-129491). O-Desmethyl Midostaurin (CGP62221, O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo[1]. Midostaurin is a multi-targeted protein kinase inhibitor?with?IC50?ranging from 22-500 nM.
Molekulargewicht:
562.57
Formel:
C28 13C6H28N4O4
Target-Kategorie:
Isotope-Labeled Compounds,PKC
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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