Octachlorodibenzo-p-dioxin (OCDD) is an environmental contaminant but is not acutely toxic. In rats, Octachlorodibenzo-p-dioxin (50 µg/kg i.v. or 50-5000 µg/kg p.o.) has a systemic elimination half-life of 3-5 months and accumulates and concentrates in the liver and adipose tissue after low-dose, repeated exposure. Repeated administration of octachlorodibenzo-p-dioxin causes increases in 7-ethoxyresorufin-O-deethylase (7-EROD) activity and total cytochrome P-450 levels[1].
Molekulargewicht:
459.75
CAS Nummer:
[3268-87-9]
Formel:
C12Cl8O2
Target-Kategorie:
Cytochrome P450
Anwendungsbeschreibung:
MCE Product type: Reference compound
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