1,2,3,6,7,8-Hexachlorodibenzofuran, CAS [[57117-44-9]]

Produktübersicht

• Artikelname: 1,2,3,6,7,8-Hexachlorodibenzofuran, CAS [[57117-44-9]]
• Artikelnummer: MCE-HY-W762015
• Hersteller Artikelnummer: HY-W762015
• Alternativnummer: MCE-HY-W762015-1MG,MCE-HY-W762015-500UG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 1,2,3,6,7,8-HxCDF

Produktbeschreibung

1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 1.47 and 1.24 nM, respectively). 1,2,3,6,7,8-Hexachlorodibenzofuran reduces weight, induces thymic atrophy, and induces the expression of genes encoding the cytochrome P450 (CYP) isoform CYP1A1 and 4-chlorobiphenyl hydroxylase in rats (EC50s = 3.2, 0.9, 0.35, and 0.21 µmol/kg, respectively)[1][2][3].

Produkteigenschaften

• Molekulargewicht: 374.86
• CAS Nummer: [57117-44-9]
• Formel: C12H2Cl6O
• Target-Kategorie: Cytochrome P450

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound