Ethyl 3,4-Dihydroxybenzoate-13C3, CAS [[1330195-40-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W778057
Hersteller Artikelnummer:
HY-W778057
Alternativnummer:
MCE-HY-W778057-1MG,MCE-HY-W778057-10MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
Protocatechuic acid ethyl ester-13C3
Ethyl 3,4-Dihydroxybenzoate-13C3 (Protocatechuic acid ethyl ester-13C3) is the 13C-labeled Ethyl 3,4-dihydroxybenzoate (HY-W016409). Ethyl 3,4-dihydroxybenzoate (Protocatechuic acid ethyl ester) is an orally effective, blood-brain barrier-permeable, competitive prolyl hydroxylase (PHD) inhibitor that inhibits the hydroxylation modification of hypoxia-inducible factor (HIF) by PHD. Ethyl 3,4-dihydroxybenzoate stabilizes HIF-1alpha by inhibiting PHD, activates downstream pathways to induce autophagy and apoptosis of tumor cells, and regulates inflammatory responses, inhibits the NF-kappaB pathway, improves vascular permeability, and promotes osteoblast differentiation. Ethyl 3,4-dihydroxybenzoate has anti-tumor, anti-hypoxic injury, and bone metabolism regulation effects. It can also be used in the research of cardiovascular protection (such as reducing myocardial ischemic damage), bone tissue engineering (promoting osteogenesis/inhibiting osteoclast differentiation), and prevention and treatment of high-altitude cerebral edema[1][2][3][4].
Molekulargewicht:
185.15
CAS Nummer:
[1330195-40-8]
Formel:
C6 13C3H10O4
Target-Kategorie:
Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
