Fmoc-PEG2-Val-Cit-PAB-OH, CAS [[2055024-59-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-W800621
Hersteller Artikelnummer:
HY-W800621
Alternativnummer:
MCE-HY-W800621-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Fmoc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine for use in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Molekulargewicht:
760.88
CAS Nummer:
[2055024-59-2]
Formel:
C40H52N6O9
Target-Kategorie:
ADC Linker
Anwendungsbeschreibung:
MCE Product type: ADC Related
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