Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding delta-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration of 10 µM. Mn(III) protoporphyrin IX chloride-containing nanobialys have been used in magnetic resonance imaging (MRI) of fibrin clots in vitro. It has also been used in the synthesis of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.
Molekulargewicht:
651.03
Reinheit:
95
CAS Nummer:
[120389-54-0]
Formel:
C34H32ClMnN4O4
Target-Kategorie:
Heme Oxygenase (HO)
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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