DL-Menthol (Racementhol) is an orally active, GABAaR positive allosteric modulator and UDP-glucuronosyltransferase (UGT) inhibitor that can cross the blood-brain barrier. DL-Menthol binds to GABAAR and exhibits an allosteric activation effect, enhancing GABA-mediated chloride influx and inhibiting neuronal excitability. DL-Menthol can induce surgical anesthesia in fish and inhibit the metabolic detoxification of tobacco carcinogens by human liver and intestinal UGT enzymes, resulting in reduced NNAL-N-Gluc production[1][2][3].
Molekulargewicht:
156.27
Reinheit:
98
CAS Nummer:
[89-78-1]
Formel:
C10H20O
Target-Kategorie:
GABA Receptor
Anwendungsbeschreibung:
MCE Product type: Natural Products
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