Express unmodified human M1 muscarinic receptor using Montana Moleculars BacMam expression system. Big Sky BacMam enables efficient, titratable transduction across a wide range of mammalian cell types-including near 100% uniform expression in HEK293 cells and robust transduction in primary or iPSC-derived cells. Expression is dose-dependent, allowing rapid assay optimization. High well-well consistency and low toxicity are well suited for diverse applications in drug discovery and GPCR biology, including compound screens, pharmacological studies, and receptor characterization. Co-express with Montana Moleculars DAG, PIP2, or Calcium assays to measure receptor activation and downstream signaling dynamics at CHRM1 in real time.
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