P-Cadherin (CDH3) Antibody, IgG1, Clone: [12H6], Mouse, Monoclonal

Produktübersicht

• Artikelname: P-Cadherin (CDH3) Antibody, IgG1, Clone: [12H6], Mouse, Monoclonal
• Artikelnummer: NBT-1001-MSM1-P1
• Hersteller Artikelnummer: 1001-MSM1-P1
• Alternativnummer: NBT-1001-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant human P-cadherin fusion protein
• Alternative Synonym: Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin

Produktbeschreibung

Recognizes a protein of 116kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [12H6]
• Molekulargewicht: 116kDa
• Isotyp: IgG1
• NCBI: 1001
• UniProt: P22223
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified P-Cadherin Mouse Monoclonal Antibody (12H6). Confirmation of Integrity and Purity of Antibody.