CD100 (Semaphorin-4D) Antibody, IgM, Clone: [133-1C6], Mouse, Monoclonal

Produktübersicht

• Artikelname: CD100 (Semaphorin-4D) Antibody, IgM, Clone: [133-1C6], Mouse, Monoclonal
• Artikelnummer: NBT-10507-MSM1-P1
• Hersteller Artikelnummer: 10507-MSM1-P1
• Alternativnummer: NBT-10507-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF
• Spezies Reaktivität: Human, Primate
• Immunogen: PHA stimulated human peripheral blood lymphocytes.
• Alternative Synonym: COLL4, Collapsin4, GR3, M sema G, MSEMA, SEMA4D, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semcl2

Produktbeschreibung

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI, Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [133-1C6]
• Molekulargewicht: 50kDa (Monomer)
• Isotyp: IgM
• NCBI: 10507
• UniProt: Q92854
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.