CD100 (Semaphorin-4D) Antibody, IgG1, Mouse, Monoclonal

Artikelnummer: NBT-10507-MSM2-P0
Artikelname: CD100 (Semaphorin-4D) Antibody, IgG1, Mouse, Monoclonal
Artikelnummer: NBT-10507-MSM2-P0
Hersteller Artikelnummer: 10507-MSM2-P0
Alternativnummer: NBT-10507-MSM2-P0-20,NBT-10507-MSM2-P0-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, Functional Studies, IF
Spezies Reaktivität: Human, Monkey, Mouse
Immunogen: PHA stimulated human peripheral blood lymphocytes
Alternative Synonym: COLL4, Collapsin4, GR3, M sema G, MSEMA, SEMA4D, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semcl2
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Klonalität: Monoclonal
Molekulargewicht: 50kDa (Monomer)
Isotyp: IgG1
NCBI: 10507
UniProt: Q92854
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Optimal dilution for a specific application should be determined.
SDS-PAGE Analysis of Purified CD100 Mouse Monoclonal Antibody (A8). Confirmation of Purity and Integrity of Antibody.