CD100 (Semaphorin-4D) Antibody, IgG1, Clone: [SEMA4D/933], Mouse, Monoclonal

Artikelnummer: NBT-10507-MSM3-P0
Artikelname: CD100 (Semaphorin-4D) Antibody, IgG1, Clone: [SEMA4D/933], Mouse, Monoclonal
Artikelnummer: NBT-10507-MSM3-P0
Hersteller Artikelnummer: 10507-MSM3-P0
Alternativnummer: NBT-10507-MSM3-P0-20,NBT-10507-MSM3-P0-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF
Spezies Reaktivität: Human, Primate
Immunogen: Human recombinant SEMA4D protein
Alternative Synonym: COLL4, Collapsin4, GR3, M sema G, MSEMA, SEMA4D, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semcl2
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Klonalität: Monoclonal
Klon-Bezeichnung: [SEMA4D/933]
Molekulargewicht: 50kDa (Monomer)
Isotyp: IgG1
NCBI: 10507
UniProt: Q92854
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Optimal dilution for a specific application should be determined.