Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody, IgG1, Clone: [D2-40], Mouse, Monoclonal

Produktübersicht

• Artikelname: Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody, IgG1, Clone: [D2-40], Mouse, Monoclonal
• Artikelnummer: NBT-10630-MSM16-P1
• Hersteller Artikelnummer: 10630-MSM16-P1
• Alternativnummer: NBT-10630-MSM16-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Resected tissue from dysgeminoma of the ovary.
• Alternative Synonym: Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8, PA2.26, Pdpn, Podoplanin, PSEC0003, PSEC0025, T1-alpha, T1A, TI1A, TIA2

Produktbeschreibung

Podoplanin is a transmembrane mucoprotein (38 kDa) recognized by the D2-40 monoclonal antibody. Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin is co-localized with VEGFR3/FLT4, another marker for lymphatic endothelial cells. Podoplanin is selectively expressed in lymphatic endothelium as well as Lymphangiomas, Kaposi,Aos Sarcomas and in subset Angiosarcomas with probable lymphatic differentiation. Podoplanin has also been shown to be expressed in Epithelioid Mesotheliomas, Hemangioblastomas and Seminomas.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [D2-40]
• Molekulargewicht: 38-43kDa
• Isotyp: IgG1
• NCBI: 10630
• UniProt: Q86YL7
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human tonsil stained with Podoplanin Mouse Monoclonal Antibody (D2-40). Inset: PBS instead of primary antibody, secondary only negative control.