Recombinant Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody, Clone: [PDPN/8875R], Rabbit, Monoclonal
Artikelnummer:
NBT-10630-RBM13-P0
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| Artikelname: | Recombinant Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) Antibody, Clone: [PDPN/8875R], Rabbit, Monoclonal |
| Artikelnummer: | NBT-10630-RBM13-P0 |
| Hersteller Artikelnummer: | 10630-RBM13-P0 |
| Alternativnummer: | NBT-10630-RBM13-P0-20 |
| Hersteller: | NeoBiotechnologies |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IF, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant fragment (around aa1-150) of human PDPN protein (exact sequence is proprietary) |
| Alternative Synonym: | Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8, |
| It recognizes a muco-protein of 38-43kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium OOas well as lymphoangiomas, OOKaposi sarcomas, OOand in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas. |
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