Recombinant Uroplakin 1A (Urothelial Differentiation Marker) Antibody, Clone: [UPK1A/8704R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant Uroplakin 1A (Urothelial Differentiation Marker) Antibody, Clone: [UPK1A/8704R], Rabbit, Monoclonal
• Artikelnummer: NBT-11045-RBM9-P1
• Hersteller Artikelnummer: 11045-RBM9-P1
• Alternativnummer: NBT-11045-RBM9-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa 100-200) of human Uroplakin 1A (UPK1A) protein (exact sequence is proprietary)
• Alternative Synonym: UP1A, UPIA, UPKA, TSPAN21

Produktbeschreibung

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.vC OO

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [UPK1A/8704R]
• Molekulargewicht: 29kDa
• NCBI: 11045
• UniProt: O00322
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.