EGFR (Epidermal Growth Factor Receptor) Antibody, IgG1, Mouse, Monoclonal

Produktübersicht

• Artikelname: EGFR (Epidermal Growth Factor Receptor) Antibody, IgG1, Mouse, Monoclonal
• Artikelnummer: NBT-1956-MSM14-P1ABX
• Hersteller Artikelnummer: 1956-MSM14-P1ABX
• Alternativnummer: NBT-1956-MSM14-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment of human EGFR protein (around aa 6-273)
• Alternative Synonym: Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5

Produktbeschreibung

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 170kDa
• Isotyp: IgG1
• NCBI: 1956
• UniProt: P00533
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1mg/ml.
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 min

Bilder

SDS-PAGE Analysis of Purified EGFR Mouse Monoclonal Antibody (R1). Confirmation of Integrity and Purity of Antibody.