AIF1 / Iba1 (Microglia Marker) Antibody, IgG2c, Clone: [MSVA-955M], Mouse, Monoclonal

Produktübersicht

• Artikelname: AIF1 / Iba1 (Microglia Marker) Antibody, IgG2c, Clone: [MSVA-955M], Mouse, Monoclonal
• Artikelnummer: NBT-199-MSM19-P0
• Hersteller Artikelnummer: 199-MSM19-P0
• Alternativnummer: NBT-199-MSM19-P0-20
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary)
• Alternative Synonym: Allograft inflammatory factor 1 (AIF1), balloon angioplasty responsive transcription (BART1), IBA1, Interferon responsive transcript 1, Ionized calcium-binding adapter molecule 1, IRT1, Microglia response factor (MRF1)

Produktbeschreibung

AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MSVA-955M]
• Molekulargewicht: 17kDa
• Isotyp: IgG2c
• NCBI: 199
• UniProt: P55008
• Formulierung: Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Bilder

Allograft inflammatory factor 1 Mouse Monoclonal Antibody (MSVA-955M) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.