Acetaldehyde dehydrogenase 1, AHD2, ALDC, Aldehyde dehydrogenase 1 soluble, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase family 1 member A1, ALDH-E1, epididymis luminal protein 12, epididymis luminal protein 9, epididymis secretory sperm binding protein Li 53e, HEL-S-53e, PUMB1, RALDH1, Retinal dehydrogenase 1
ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Western Blot (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for
Formalin-fixed, paraffin-embedded human sarcoma
Formalin-fixed, paraffin-embedded human breast carcinoma in tonsil stained with ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human sarcoma in tonsil stained with ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human colon carcinoma in tonsil stained with ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793).
Formalin-fixed, paraffin-embedded human colon carcinoma in tonsil stained with ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793).
Western Blot Analysis of HEPG-2 cell lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793).
SDS-PAGE Analysis Purified ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793). Confirmation of Integrity and Purity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using E-Cadherin Mouse Monoclonal Antibody (CDH1/4585). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD&apos,s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD&apos,s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Western Blot Analysis of Human Brain tissue lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793).
Western Blot Analysis of Human Brain tissue lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/4793).
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