Recombinant FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Antibody, Clone: [FABP5/6353R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Antibody, Clone: [FABP5/6353R], Rabbit, Monoclonal
• Artikelnummer: NBT-2171-RBM3-P1ABX
• Hersteller Artikelnummer: 2171-RBM3-P1ABX
• Alternativnummer: NBT-2171-RBM3-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant human full-length FABP5 protein
• Alternative Synonym: FABP5, E-FABP, EFABP, PA-FABP, PAFABP

Produktbeschreibung

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [FABP5/6353R]
• Molekulargewicht: 15kDa
• NCBI: 2171
• UniProt: Q01469
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC

Bilder

Formalin-fixed, paraffin-embedded human liver metastasized to colon stained with FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Western Blot Analysis of HeLa lysate using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Western Blot Analysis of Raji lysate using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

SDS-PAGE Analysis Purified FABP5 Rabbit Recombinant Monoclonal Antibody (FABP5/6353R). Confirmation of Purity and Integrity of Antibody.

Western Blot Analysis of brain and skin tissue lysates of different species using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).

Western Blot Analysis of Human Brain, Human Skin, HeLa and Raji lysates using FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R).